Isotretinoin is acting where others are helpless. But what is the other side of the shield? This is the main factor why isotretinoin is prescribed. There is maybe no other drug, which is as potent as this one. There is maybe no other drug, which can cope with such severe acne, as isotretinoin can. It is often given when all other preparations have shown their impotence. Powerlessness of other preparations sometimes leads to isotretinoin.

Isotretinoin affects all stages of development of acne. The drug influences on many factors that become acne-causers. First, it reduces production of skin oil, which is one of the major factors. From one side it is good, and it is clear why – because when there is too much oil, it comes into skin pores, which subsequently leads to appearance of acne. But from the other side…it will be enough just to think over the actual mechanism, how isotretinoin reduces the production of oil.

Of course, this can be done, first of all, by limitation of activity of the units that produce that oil, namely sebaceous glands. So it happens that isotretinoin just slows down their development and suppresses their activity, so that they produce less oil. You may not agree but I think that when some preparation, which is not related to any natural means, suppresses activity of some cells or some organs of the organism, it doesn’t inspire me at all.

There is even some division into isotretinoin and other kinds of acne treatment. If long-term courses of antibacterial medications do not bring any result, then isotretinoin is prescribed. If after several successful courses relapses reappear, then isotretinoin is prescribed. If scars tend to appear after acne, isotretinoin is prescribed.

However, because of such strength isotretinoin is impacting not only acne and its causes, but also the organism in a whole. This is a cause of side effects, some of which are very severe so that, for example, it is forbidden to take isotretinoin during pregnancy.

So everything is not so simple with isotretinoin.